Cavitary bone defects are created following curettage and debridement of benign bone tumors or malignancies. In order to properly heal these bone defects, the resultant voids must be filled with bone graft or substitute material to facilitate bone healing and prevent infiltration of non-osseous fibrous tissue. Due to the inherent drawbacks of autologous bone graft (e.g. supply limitations, variable quality, additional operative time, patient morbidity), synthetic bone graft substitutes have been developed and are available for clinical use. However, despite the availability of a wide array of bone graft substitutes, the quest for an ideal bone graft remains elusive.
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