The ExtremiFix Cannulated Screw System - Midsize & Large is indicated for use in bone reconstruction, osteotomy, arthrodesis, and fracture fixation of foot, ankle, and long bones (upper and lower extremity). Screws in the system are offered in three diameters: 4.5 mm, 5.5 mm, and 6.5 mm to accommodate various fracture patterns and patient anatomy. Screws are offered as 1/2 or 1/3 threaded, headed or headless, in a variety of lengths intended for applications in the midfoot, hindfoot, and ankle.